The O-Shot® (PRP Therapy for Sexual Wellness & Urinary Symptoms)

The O-Shot® is an in-office procedure that uses platelet-rich plasma (PRP) derived from your own blood to support tissue health and healing in sensitive vaginal and clitoral tissues. Many patients seek this treatment to improve sexual function, vaginal comfort, or mild urinary leakage. Dr. Patrick Nosti is one of a limited number of physicians specially trained, certified and licensed to administer this revolutionary new treatment.

What is PRP?

Platelet-rich plasma (PRP) is a concentration of platelets obtained from a small sample of your own blood. Platelets contain growth factors that play a role in tissue repair and regeneration. PRP has been used for years in other areas of medicine, including orthopedics, sports medicine, and wound healing.

Female doctor consulting with patient in clinic office

What is the O-Shot® and how is it performed?

The O-Shot® involves injecting PRP into targeted areas of the vagina and clitoral region with the goal of:

Supporting tissue health
Enhancing blood flow
Potentially improving nerve sensitivity

The procedure is performed in the office and typically takes about 30–45 minutes from start to finish.

What symptoms may the O-Shot® help with?

Patients most commonly inquire about the O-Shot® for:

Decreased sexual sensation or arousal
Difficulty achieving orgasm
Vaginal dryness or discomfort
Mild stress urinary incontinence (leakage with coughing, laughing, or exercise)

This office has a very calming, quiet and Zen atmosphere. They’ve always been on time for my appts. The staff are very professional, personable, caring. Thank you for a job well done.

-Susan D.

Am I a candidate for the O-shot?

Not all patients are good candidates for the O-shot as both sexual dysfunction and urinary incontinence are multifactorial. At you initial consultation Dr. Nosti will review your history and perform an exam to determine what treatments are best to address your concerns and achieve your goals.

What happens during the procedure?

A small blood sample is drawn from your arm
The blood is processed in a centrifuge to isolate PRP
A topical numbing agent is applied
PRP is injected into specific vaginal and clitoral areas

Most patients describe the procedure as well tolerated, with mild pressure or brief stinging.

Is the O-Shot® safe?

Because PRP comes from your own blood, the risk of allergic reaction is very low. However, as with any injection procedure, potential risks include:

Temporary swelling or bruising
Mild discomfort or pressure
Spotting
Infection (rare)

PRP treatments like the O-Shot are not FDA approved for aesthetic use because the regulatory agency doesn’t govern blood biologics. However, as a certified provider of the O-Shot, Dr. Nosti uses FDA-approved devices to prepare the PRP used for the O-Shot.

What to expect during recovery

There’s no real recovery time, aftercare, or restrictions following an O-Shot procedure. Normal sensation should return to the treated areas a few hours after the procedure, once the numbing cream has worn off. Patients can resume all activities, including sexual activity, the same day, but there may be light spotting from the needle injections.

When will I see results?

Some patients notice changes within a few weeks
Others may take 2–3 months
Results, if present, are typically temporary and may last 6–12 months

Repeat treatments are sometimes requested, though optimal treatment intervals are patient dependant.

Is the O-Shot® covered by insurance?

No. The O-Shot® is considered an elective procedure and cost $1500. It is not covered by insurance.

What if the O-shot doesn’t work?

The O-shot is highly effective for the vast majority of patients. However, like any intervention, the O-shot does not work for all patients. If you have the procedure and after 3-4 months it does not produce the desired effect, Dr. Nosti will reevaluate you. An additional treatment may be recommended at no cost to you or your money will be refunded. There are other treatments available for both sexual dysfunction and incontinence all of which are offered at Urogynecology of Kansas City. These treatments will be reviewed and discussed at that length. Ultimately, we are here to make you better and if the O-shot does not help we will work to find an alternative.

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   Dana Smith 
 September 25, 2026
 
 
 Trustindex verifies that the original source of the review is Google. I can't recommend Dr. Nosti and the team at Urogynecology of Kansas City enough. I had surgery with him last month, and from my very first evaluation appointment through recovery, the entire experience exceeded my expectations. Dr. Nosti took the time to listen, explain my options clearly, and made me feel confident and comfortable with my decision to move forward with surgery. The surgery itself went smoothly, and my recovery has been great.

Every member of the staff was kind, professional, and attentive at every visit. I'm so glad I made that first appointment to get evaluated — it's made a real difference in my quality of life. I would give Dr. Nosti and his team a 10/10 recommendation to anyone considering care with this practice.
  
 
      
   Patty Cowan 
 September 23, 2026
 
 
 Trustindex verifies that the original source of the review is Google. Latasha Reed was great to work with. She was very thorough and took the time to listen to everything that was going on. She went beyond the scope of the initial reason I was coming to see her and helped me with another concern. I would highly recommend her.
  
 
      
   Shawn Kyndesen 
 September 11, 2026
 
 
 Trustindex verifies that the original source of the review is Google. I had my first visit with Kellie James, CRNP and she listened to all my concerns. She gave me a plan to help my urinary in-continuance. She was so easy to talk to!
I am so thankful that I saw her. My life has changed for the better!  SKK
  
 
      
   charnice burk 
 September 4, 2026
 
 
 Trustindex verifies that the original source of the review is Google. Dr. Nosti is great! I felt very confident in his work. He has done 2 procedures for me and both have gone so smooth. He tells you what to expect and has a plan for those things. I would refer him to anyone having gynecological issues that they need surgery for. Thanks Dr. Nosti!!
  
 
      
   Deb Hundley 
 August 26, 2026
 
 
 Trustindex verifies that the original source of the review is Google. As a Provider in the region I self referred to Dr. Nosti for female pelvic organ prolapse and stress incontinence. From the time I walked in the door for my initial consult to my post-op surgical follow up the process has been seamless. Any hiccups were anticipated and a plan was in place prior. I’ve been nothing but happy with this process and my results.
  
 
      
   Kathryn Gonzalez 
 August 26, 2026
 
 
 Trustindex verifies that the original source of the review is Google. Everyone is so professional and Dr. Nosti is incredible.  Surgery went well.  I feel more confident.
  
 
      
   Rose Hamilton 
 August 25, 2026
 
 
 Trustindex verifies that the original source of the review is Google. This place was amazing, I was treated kindly and softly, everything explained to me as we went, my options and things to help till my next appointment.
The office itself is soft, clean, and quiet to help you feel more relaxed in an uncomfortable situation. Everyone was very friendly and respectful. I highly recommend this office.
Dr Stork was very friendly, took her time, explained everything and presented my options, pros and cons for each and let me make the choice. She was light-hearted and helped me feel at ease.
  
 
      
   Elaine Smith 
 August 16, 2026
 
 
 Trustindex verifies that the original source of the review is Google. Dr Nosti is wonderful, I would recommend him to any of my friends.  His office staff are kind, courteous and professional.  Highly recommend if you need urogynecology services!!
  
 
      
   Ashlee White 
 August 13, 2026
 
 
 Trustindex verifies that the original source of the review is Google. I have dealt with IC and bladder pain for the last 3 years. Went to a urologist for years and tried anything he threw at me but after years of suffering and plenty of my own research (spiraling), I found Latasha online. She is the first provider that made me feel seen and heard and actually helped me feel better. Thank you, Latasha! ❤️
  
 
      
   Colleen Dublin 
 August 11, 2026
 
 
 Trustindex verifies that the original source of the review is Google. Dr. Nosti and LaTasha are excellent practitioners. They are a busy practice but always have time to make you feel like you're the only patient. (I wouldn't recommend a practice that isn't busy... if it's not, the practitioners aren't any good). The staff is excellent, too.
I'm a bit of an expert when judging urologists... I'm in my 50's and was born with a bladder condition. Needless to say, I've seen many urologists since childhood (I move around a lot).