The O-Shot® (PRP Therapy for Sexual Wellness & Urinary Symptoms)

The O-Shot® is an in-office procedure that uses platelet-rich plasma (PRP) derived from your own blood to support tissue health and healing in sensitive vaginal and clitoral tissues. Many patients seek this treatment to improve sexual function, vaginal comfort, or mild urinary leakage.  Dr. Patrick Nosti is one of a limited number of physicians specially trained, certified and licensed to administer this revolutionary new treatment.

What is PRP?

Platelet-rich plasma (PRP) is a concentration of platelets obtained from a small sample of your own blood. Platelets contain growth factors that play a role in tissue repair and regeneration.  PRP has been used for years in other areas of medicine, including orthopedics, sports medicine, and wound healing.

Female doctor consulting with patient in clinic office

What is the O-Shot® and how is it performed?

The O-Shot® involves injecting PRP into targeted areas of the vagina and clitoral region with the goal of:

  • Supporting tissue health
  • Enhancing blood flow
  • Potentially improving nerve sensitivity

The procedure is performed in the office and typically takes about 30–45 minutes from start to finish.

What symptoms may the O-Shot® help with?

Patients most commonly inquire about the O-Shot® for:

  • Decreased sexual sensation or arousal
  • Difficulty achieving orgasm
  • Vaginal dryness or discomfort
  • Mild stress urinary incontinence (leakage with coughing, laughing, or exercise)

This office has a very calming, quiet and Zen atmosphere. They’ve always been on time for my appts. The staff are very professional, personable, caring. Thank you for a job well done.

-Susan D.

Am I a candidate for the O-shot?

Not all patients are good candidates for the O-shot as both sexual dysfunction and urinary incontinence are multifactorial.  At you initial consultation Dr. Nosti will review your history and perform an exam to determine what treatments are best to address your concerns and achieve your goals.

What happens during the procedure?

  1. A small blood sample is drawn from your arm
  2. The blood is processed in a centrifuge to isolate PRP
  3. A topical numbing agent is applied
  4. PRP is injected into specific vaginal and clitoral areas

Most patients describe the procedure as well tolerated, with mild pressure or brief stinging.

Is the O-Shot® safe?

Because PRP comes from your own blood, the risk of allergic reaction is very low. However, as with any injection procedure, potential risks include:

  • Temporary swelling or bruising
  • Mild discomfort or pressure
  • Spotting
  • Infection (rare)

PRP treatments like the O-Shot are not FDA approved for aesthetic use because the regulatory agency doesn’t govern blood biologics.  However, as a certified provider of the O-Shot, Dr. Nosti uses FDA-approved devices to prepare the PRP used for the O-Shot.

What to expect during recovery

There’s no real recovery time, aftercare, or restrictions following an O-Shot procedure.  Normal sensation should return to the treated areas a few hours after the procedure, once the numbing cream has worn off. Patients can resume all activities, including sexual activity, the same day, but there may be light spotting from the needle injections.

When will I see results?

  • Some patients notice changes within a few weeks
  • Others may take 2–3 months
  • Results, if present, are typically temporary and may last 6–12 months

Repeat treatments are sometimes requested, though optimal treatment intervals are patient dependant.

Is the O-Shot® covered by insurance?

No. The O-Shot® is considered an elective procedure and cost $1500.  It is not covered by insurance.

What if the O-shot doesn’t work?

The O-shot is highly effective for the vast majority of patients.  However, like any intervention, the O-shot does not work for all patients.  If you have the procedure and after 3-4 months it does not produce the desired effect, Dr. Nosti will reevaluate you.  An additional treatment may be recommended at no cost to you or your money will be refunded.  There are other treatments available for both sexual dysfunction and incontinence all of which are offered at Urogynecology of Kansas City.  These treatments will be reviewed and discussed at that length.  Ultimately, we are here to make you better and if the O-shot does not help we will work to find an alternative.

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Deb Hundley profile picture
Deb Hundley
August 26, 2026
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As a Provider in the region I self referred to Dr. Nosti for female pelvic organ prolapse and stress incontinence. From the time I walked in the door for my initial consult to my post-op surgical follow up the process has been seamless. Any hiccups were anticipated and a plan was in place prior. I’ve been nothing but happy with this process and my results.
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Kathryn Gonzalez
August 26, 2026
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Everyone is so professional and Dr. Nosti is incredible. Surgery went well. I feel more confident.
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Rose Hamilton
August 25, 2026
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This place was amazing, I was treated kindly and softly, everything explained to me as we went, my options and things to help till my next appointment. The office itself is soft, clean, and quiet to help you feel more relaxed in an uncomfortable situation. Everyone was very friendly and respectful. I highly recommend this office. Dr Stork was very friendly, took her time, explained everything and presented my options, pros and cons for each and let me make the choice. She was light-hearted and helped me feel at ease.
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Elaine Smith
August 16, 2026
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Dr Nosti is wonderful, I would recommend him to any of my friends. His office staff are kind, courteous and professional. Highly recommend if you need urogynecology services!!
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Ashlee White
August 13, 2026
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I have dealt with IC and bladder pain for the last 3 years. Went to a urologist for years and tried anything he threw at me but after years of suffering and plenty of my own research (spiraling), I found Latasha online. She is the first provider that made me feel seen and heard and actually helped me feel better. Thank you, Latasha! ❤️
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Colleen Dublin
August 11, 2026
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Dr. Nosti and LaTasha are excellent practitioners. They are a busy practice but always have time to make you feel like you're the only patient. (I wouldn't recommend a practice that isn't busy... if it's not, the practitioners aren't any good). The staff is excellent, too. I'm a bit of an expert when judging urologists... I'm in my 50's and was born with a bladder condition. Needless to say, I've seen many urologists since childhood (I move around a lot).
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Jennifer Sada
August 2, 2026
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This office is extremely clean and well organized. I never had to wait more than two minutes and the staff is very friendly and professional. I felt fully supported by Kellie James and Dr. Nosti at every step of the diagnosis and treatment.
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Lisa Kurz
July 20, 2026
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I had the best experience with Dr. Nosti, he’s so caring and made me feel very comfortable. I’ve never felt better and my life is back to normal again! He is so wonderful and explained everything. I’m so happy I didn’t wait and his staff at his office and at the hospital were amazing!!
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Lynette Beebe
July 20, 2026
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I was struggling. Latasha Reed and Dr. Nosti were so helpful. I can go places without accidents.
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Leesa Gavin
July 20, 2026
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I wish I did this 5 years ago, it has made me be free of the toilet as often as I was sitting on it, I now can walk by and do other things in my life! Thank you , Dr. Patrick Nosti

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